Clinically depressed people may not be able to experience any joy or hope. They cannot control their own thought processes and cannot switch from negative thoughts and try to “cheer up”. If you tell someone who is depressed to do so, you may only alienate the person and jeopardize your chances of reaching out to that person in any way. Everyone gets depressed at some point in their life, but clinical depression is different. It would be really good if you would educate yourself as to what clinical depression is all about so that you can understand your friend and what she is going through. Finding medical care for those that are clinically depressed is very important. Gently nudge her to get help. You may want to speak to her family to see how they can help. In the meantime, you can also pray and ask God to give you wisdom as to how to pray effectively for your friend.